CEO Today - March 2023

www.ceotodaymagazine.com 22 itself. This not only energizes cells across the entire wound surface, it also effectively kills bacteria. V.Dox Technology uses electricity to do its job whereas the current Standard Of Care (SOC), silver antimicrobial wound dressings, release a high volume of silver ions to do their job. As the only microcell battery-powered technology of its kind, Vomaris’s V.Dox Technology is uniquely poised to disrupt the current SOC, while seamlessly and cost-effectively integrating into existing clinical care protocols. In addition to a strong IP portfolio, we have a large body of published evidence (26 peer-reviewed publications), demonstrating the technology’s outstanding healing and antimicrobial impact. What are some of the sector’s key challenges? Effective wound management and healing is a universal problem that is costly, both economically and in terms of human suffering: - Over 1.5 million people suffer each year from surgical site infections in the US alone. - 6.7 million Americans have chronic wounds. - Importantly, close to 80% of non-healing and infected wounds involve a biofilm infection. When bacteria shelter themselves in a biofilm coating, it protects them from antibiotics and immune system attack, making them notoriously difficult to treat. In managing acute and chronic wounds, there are a couple significant challenges the industry’s standard of care has yet to overcome: the use of potentially cytotoxic levels of silver ions for antimicrobial impact, and the ability to prevent or disrupt biofilm infections – both of which V.Dox Technology effectively addresses. The advanced wound care segment of the global wound care market approximates $7 billion. And yet, the majority of currently available bandages and wound care dressings have been in use for nearly a century, with little to no innovation. We need to do better for our patients. And what about the opportunities? For years, the antimicrobial dressings in the market have used silver ion release to kill bacteria. Where competitive silver dressings fall short is that: they aren’t able to address biofilm without adding chemicals, and they have not demonstrated the ability to impact cell migration and re-epithelialization. V.Dox Technology delivers a combination of benefits that no competitive antimicrobial wound dressing can claim: 1. Using biomimicry, the microcell batteries generate electricity within the same physiologic range that wounded skin uses to drive healing (aka the ‘current of injury’). This supports the skin’s natural healing process and has been shown to accelerate the rate of cell migration and re-epithelialisation. 2. It is a broad-spectrum antimicrobial agent that has also demonstrated impact against antibiotic-resistant bacteria and biofilm to Q Q h Q h THE CEO INTERVIEW

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